Soft and Bio Materials Lab
Assistant Prof. Chanjoong Kim, Ph. D
Chemical Physics Interdisciplinary Program, Liquid Crystal Institute 356-362
Kent State University, PO Box 5190, Kent, OH 44242  

We utilized chemically inert glass capillaries based microfluidic device to generate monodisperse emulsions, colloids, or liposomes. This technique can be used to encapsulation of drug, cell or active biomaterials in lipid vesicle or bio gels for drug delivery and bioreactor applications.

  1. Microfluidics by H. Yan, W. W. Jeoung, C. Kim

We have produced monodisperse liquid crystal elastomer (LCE) colloidal particles.  The LCE particles are composed of siloxane polymer backbone, mesogen on the side and crosslinkers. LCE materials are provided by the New Liquid Crystal Materials Facility (NLCMF).

  1. Colloidal Liquid Crystal Elastomers by S. Mukherjee , C. Kim

  1. Thermosensitive Gelatin Microgels Based by B. Sung, S. Gandhi, C. Kim

We have mixed nematic liquid crystal with 10v% colloidal particles. We find that the composite self-assembled to a 3D hierarchical “FERN” structure. We are exploring various conditions such as cooling rates, particle sizes and anchoring conditions to find the mechanism of the self-assembly of particles in anisotropic fluid.

  1. Colloidal Liquid Crystal Composites by L. Zou, J. Y. Hwang, C. Kim

* In collaboration with Dr. Min Ho Kim at KSU Biology

The objective of this project is to explore novel strategies for the synthesis of mesoporous silica microencapsulation for biomedical applications such as drug delivery and controlled release. They have been used for wide range of applications, such as drug delivery systems, molecular and cellular encapsulation, and microreactor.

  1. Microbottles by H. Yan, C. Kim

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We are developing a thermoresponsive, colloidal and fully biocompatible & biodegradable hydrogel microsphere with a tunable drug release property by physically entrapping temperature-sensitive polymer chains in a 3D-crosslinked gelatin network.

We study 2D colloids in solid and hexatic phases that show seemingly Fickian but strongly heterogeneous dynamics. But dynamics is still heterogeneous significantly with non-Gaussian Gs(r, t) and several peaks that may be related to dynamics clusters of discs with discretized mobility.

  1. Dynamics of 2D colloidal system by C. Kim

  1. High Speed Defect Inspection of Defects on Flat panels by M.-S. Kim, C. Kim

We are developing a novel inspection method to characterize surface defects, which is both optimally efficient and nondestructive, using the Laser surface light scattering that is caused by surface roughness. Above pictures demonstrate that defects larger than 200 nm can be detected in line. This line scanning system has a high  throughput > 5 cm/sec. We can inspect the whole surface of a 2” wafer in 2 seconds!

We are investigating the effects of size, shape and surface modification of magnetic nanoparticles (MNPs) that can be used in biomedical applications such as magnetic resonance imaging (MRI), tissue engineering, hyperthermia, and gene and drug delivery.

  1. Modification of magnetic nanoparticles for Biomedical Applications

    by L. Zou, H. Yan, C. Kim

* This project is supported by the NSF (OISE-1004228).

Our study has shown that a surface modification process with PEG produces non-bleaching photoluminescent (PL) biocompaticle coatings on the magnetic nanoparticles without any addition of fluorophores, such as quantum dots or fluorescent dyes. Using this simple method, it is possible to produce dual-mode bio-imaging (fluorescence and magnetic resonance imaging) contrast agents. In-vivo tests on mice with the PL-MNPs show that PL-MNPs have excellent biocompatibility. In addition, even without the magnetic nanoparticles, PL-PEGs can be produced by a simple process. The remarkable non-photobleaching property of the PL-PEGs was confirmed by long time light exposure.

As a low-cost, bio-safe, non-bleaching alternative of conventional fluorophores, the applications of the PL-PEGs and PL-MNPs cover a wide range from biomedical diagnostics and therapeutics to industrial materials.

* In collaboration with Dr. B. J. Sung at Sogang University

* In collaboration with Dr. P. Palffy-Muhoray Kim at KSU LCI

We synthesized fluorescently-labeled polymer particles in a density- and index- matched organic solvent. These particles can be used to study model atomic systems.

  1. Colloidal particle synthesis by L. Zou, C. Kim